Advanced Techniques

Available Advanced Techniques

The field of chemical crystallography has moved on rapidly in the last decade. With modern instrumentation, sophisticated software and expert approaches it is now possible to go beyond structural characterisation and explore the solid state in high resolution and under dynamic conditions. These approaches can provide considerable insight into a range of chemical problems. The NCS can now perform exploratory, pilot studies using these techniques and with a view to follow-on work being larger, self-supporting collaborations. 

The techniques we currently support are –

Using our very rapid data collection capability over a temperature range from 1.5K to 500K we can capture multiple data sets in order to follow thermal behaviour, phase transitions, magnetism and reactivity.

Using Diamond Anvil Cell technology we can subject a crystal to pressure up to ~20 GPa, which can produce phase transitions and structural change.

We can systematically expose crystals to a range of different gasses in order to explore porosity or induce solid-state reactions.

Accurate, high resolution data collections enable refinement of electron distribution across the whole crystal. This provides insight into the nature of bonding and intermolecular interactions, with the ability to then derive properties such as energies of interaction.

Molecular structural characterisation of nanoscale amounts of uncrystallisable analytes.

Encapsulated Nanodroplet Crystallisation (ENaCt) is a new approach to the crystallisation of small organic molecules using high-throughput robotics.

Please contact us to discuss details if you require these kinds of study